2021 World Conference on Lung Cancer (Posters)-FP07. Diagnostic Potential of Novel Mesothelioma-Specific MicroRNAs

FP07. Diagnostic Potential of Novel Mesothelioma-Specific MicroRNAs

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Video Summary

The study aims to investigate the diagnostic potential of novel mesothelioma-specific microRNAs (MPMs) in differentiating malignant pleuromesothelioma (MPM) from other cancers. The study validates the findings of a previous study by Martinez et al., which identified 154 novel MPM microRNAs. An independent cohort of patients with MPM and non-MPM cases, including lung and breast cancers, is being used to evaluate the diagnostic potential. The researchers have successfully detected the microRNAs in the samples and observed significantly increased expression in MPM compared to non-malignant tissue. Further analysis and optimization of PCR conditions will be done to validate a molecular classifier for discriminating MPM from other cancers.

Asset Subtitle

Michaela B Kirschner

Meta Tag

Speaker Michaela B Kirschner

Topic Mesothelioma, Thymoma and Other Thoracic Malignancies

Keywords

mesothelioma-specific microRNAs

malignant pleuromesothelioma

novel MPM microRNAs

diagnostic potential

MPM vs. non-MPM cancers