2022 World Conference on Lung Cancer (Posters)-P1.02-03. Budget Impact Analysis of Volume CT Lung Cancer Screening Based on NELSON Study Outcomes in Europe

P1.02-03. Budget Impact Analysis of Volume CT Lung Cancer Screening Based on NELSON Study Outcomes in Europe

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Lung cancer is a leading cause of cancer-related deaths worldwide, including Europe. Volume CT screening has the potential to detect lung cancer early and reduce mortality rates in high-risk populations. However, concerns about the economic impact of implementing nationwide lung cancer screening programs remain. This study aimed to estimate the financial impact and clinical outcomes of implementing such a program based on the NELSON study outcomes in 28 European countries.<br /><br />A budget impact model was developed to demonstrate the financial and health-related consequences of implementing a national lung cancer screening program compared to the current standard of care. The model considered the eligible population based on NELSON inclusion criteria and used NELSON screening outcomes.<br /><br />The results showed that screening nearly 21 million people in Europe could avert 18,169 premature lung cancer deaths. The estimated budget impact for this screening program was approximately 937.3 million, assuming a 50% uptake rate. The cost per premature lung cancer death averted was 51,588, and the cost per screening participant was 45.<br /><br />Sensitivity analysis revealed that the main factors affecting the total budget impact were the unit costs for CT scans, stage I and stage IV treatment costs. The study also found a significant shift in lung cancer stage from stage IV to stage I due to lung cancer screening with volume CT, which moves patients from advanced to curative stages.<br /><br />In conclusion, implementing lung cancer screening with volume-based low-dose CT in 28 European countries could avert over 18,000 premature lung cancer deaths at a budget of approximately 937 million. This highlights the potential clinical benefits of implementing such a program at a reasonable cost.

Asset Subtitle

Xuanqi Pan, Netherlands

Meta Tag

Speaker Xuanqi Pan, Netherlands

Topic Early Detection and Screening - Implementation

Keywords

lung cancer

cancer-related deaths

Europe

Volume CT screening

early detection

mortality rates

high-risk populations

economic impact

clinical outcomes

budget impact