2022 World Conference on Lung Cancer (Posters)-P2.08-01. Real-world barriers to clinical trial enrollment as reported by U.S. lung cancer patients and community cancer centers

P2.08-01. Real-world barriers to clinical trial enrollment as reported by U.S. lung cancer patients and community cancer centers

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A new study examined the factors that contribute to low enrollment rates in clinical trials for cancer patients in the United States. The study found that only 6% to 8% of cancer patients participate in clinical trials, despite guidelines recommending trial consideration for all patients. The study analyzed data from a network of community cancer centers and patient-reported data from a personalized trial navigation program.<br /><br />The findings revealed that community oncology practices referred a median of 10% of patients to specific trials, and of those, a median of 16% actually enrolled. Common reasons for patients not enrolling in trials included lack of an appropriate match or patient-level factors such as low understanding of trials or patient refusal to join.<br /><br />The study also identified potential drivers for increasing trial enrollment, including increasing local trial availability and implementing patient awareness and education efforts. It was found that among participants in the personalized trial navigation program, 29% had not discussed trials before participating, but 95% had subsequent conversations with their providers about trials after navigation.<br /><br />The study highlights the need for greater access to local trials and improved patient education about the benefits of participating in clinical trials. Efforts to increase trial availability and facilitate remote access to distant trials could also help boost enrollment rates. The study suggests that personalized trial navigation programs can play a crucial role in increasing enrollment by providing education and support to patients.<br /><br />Overall, the study emphasizes the importance of addressing barriers such as lack of appropriate trials and inadequate patient awareness/education in order to improve clinical trial enrollment rates in cancer patients.

Asset Subtitle

Andrew Ciupek, United States

Meta Tag

Speaker Andrew Ciupek, United States

Topic Patient Advocacy

Keywords

clinical trials

enrollment rates

cancer patients

United States

factors

low understanding

patient refusal

trial availability

patient education

trial navigation program