2022 World Conference on Lung Cancer (ePosters)-EP02.03-012. Peri-operative and Oncologic Outcomes after Robotic-Assisted Segmentectomy at a NCI-designated Cancer Center

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In a study conducted at the H. Lee Moffitt Cancer Center and Research Institute, researchers examined the outcomes of robotic-assisted segmentectomy for non-small cell lung cancer (NSCLC). The study aimed to assess the perioperative and oncologic outcomes of this procedure and investigate the prognostic implications of preoperative PET-scan standard uptake value (SUV) in relation to tumor stage, differentiation, and recurrence patterns.<br /><br />A total of 166 patients who underwent robotic-assisted segmentectomy between 2010 and 2021 were included in the retrospective analysis. The main outcomes of interest were overall survival (OS) and recurrence-free survival (RFS). Kaplan-Meier curves were used to visualize the survival rates, which were further stratified according to tumor histology, pathologic stage, and standard uptake value.<br /><br />The results showed that robotic-assisted segmentectomy had reasonable perioperative and oncologic outcomes. The median operative duration was 168.5 minutes, and the median estimated blood loss was 50 mL. The conversion rate to thoracotomy was 3.9%, and intraoperative complications occurred in 2.9% of cases. The hospital length of stay was 3 days, and the chest tube duration was also 3 days for most patients.<br /><br />The most common post-operative complications were atrial fibrillation, persistent air leak, pneumonia, and hypoxia. However, the 30-day mortality rate was 0%. The recurrence rate for this cohort was 28.4%, with a median time to recurrence of 353 days. The median time to mortality was 505 days.<br /><br />Furthermore, the study found statistically significant associations between SUV and various factors such as tumor histology, tumor grade, lymphovascular invasion, viscero-pleural invasion, recurrence, and site of recurrence. However, there was no association between pathologic stage and preoperative SUV in this patient cohort.<br /><br />In conclusion, robotic-assisted segmentectomy for NSCLC showed promising perioperative and oncologic outcomes. The study also highlighted the prognostic significance of preoperative SUV in relation to tumor characteristics and recurrence patterns. This information can help inform treatment decisions and improve patient outcomes.

Asset Subtitle

Jobelle Joyce Anne Baldonado

Meta Tag

Speaker Jobelle Joyce Anne Baldonado

Topic Early Stage Non-small Cell Lung Cancer - Surgery

Keywords

robotic-assisted segmentectomy

non-small cell lung cancer

perioperative outcomes

oncologic outcomes

preoperative SUV

tumor characteristics

recurrence patterns

overall survival

recurrence-free survival

tumor histology