2022 World Conference on Lung Cancer (ePosters)-EP04.02-001. Sex as a Potential Independent Prognostic Factor in Non-Small Cell Lung Cancer Survival

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A recent study conducted in Canada aimed to evaluate the impact of sex on the survival of patients with non-small cell lung cancer (NSCLC). Lung cancer is the leading cause of cancer-related death in Canada, with NSCLC being the most common type of lung cancer. Previous studies have shown that NSCLC survival can vary based on factors such as stage at diagnosis, age, histology, smoking status, and molecular biomarkers. Some studies from other countries have also suggested that there may be differences in NSCLC survival based on sex, with males having decreased overall survival compared to females.<br /><br />The study utilized real-world data from the Glans-Look Lung Cancer Research program database, which contains information on patients diagnosed with lung cancer in Alberta. The data included demographic, clinical, pathological, treatment, and outcome information. Descriptive statistics and survival analyses were conducted to assess the impact of sex on NSCLC survival.<br /><br />The findings of the study revealed that females with NSCLC tended to have longer survival than males with NSCLC. This difference in survival was observed across all stages of NSCLC diagnosis and persisted even after adjusting for other prognostic factors. These results are consistent with previous studies conducted in other countries.<br /><br />The study also provided additional insights into the characteristics of NSCLC patients in Alberta. The majority of patients were diagnosed at a metastatic stage, with adenocarcinoma being the most common histological subtype. Females were more likely to be diagnosed at earlier stages of the disease and with adenocarcinoma histology.<br /><br />Overall, the study highlights the importance of considering sex as an independent prognostic factor for NSCLC survival. Further research is needed to better understand the underlying reasons for the observed differences in survival and to develop targeted approaches for improving outcomes for both male and female NSCLC patients.

Asset Subtitle

Chelsea Ann Ford-Sahibzada

Meta Tag

Speaker Chelsea Ann Ford-Sahibzada

Topic Global Health, Health Services Research, and Health Economics - Support to Patients and Staff

Keywords

Canada

sex

survival

non-small cell lung cancer

NSCLC

leading cause

cancer-related death

stage at diagnosis

age

histology