2022 World Conference on Lung Cancer (ePosters)-EP04.02-004. The Patient Impact of Liquid Biopsy - Health-Related Quality of Life in Patients Undergoing Liquid Biopsy for Advanced Non-Small Cell Lung Cancer

EP04.02-004. The Patient Impact of Liquid Biopsy - Health-Related Quality of Life in Patients Undergoing Liquid Biopsy for Advanced Non-Small Cell Lung Cancer

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This document discusses a study that focused on the impact of liquid biopsy testing on the quality of life in patients with advanced non-small cell lung cancer (NSCLC). Liquid biopsy, which involves analyzing plasma cell-free DNA, has been shown to provide more comprehensive molecular profiling and faster results compared to traditional tissue biopsies. The study included two cohorts of NSCLC patients: treatment-naïve patients and patients who had progressed on targeted therapy. Quality of life was assessed using the EQ-5D-5L instrument, which measures overall health. <br /><br />The results of the study showed that comprehensive liquid biopsy testing improved the quality of life for treatment-naïve patients by identifying more candidates for first-line targeted therapy. Patients who received targeted therapy had better quality of life compared to those who received non-targeted therapy. Within the non-targeted therapy group, patients receiving immunotherapy or a combination of chemotherapy and immunotherapy had improved quality of life compared to those receiving chemotherapy alone. <br /><br />The study also assessed patients' willingness to pay for liquid biopsy testing. The majority of patients surveyed were willing to pay for the testing, indicating that they saw value in the use of liquid biopsy in their treatment. <br /><br />Overall, the study suggests that liquid biopsy testing has a positive impact on the quality of life in advanced NSCLC patients. It provides more accurate molecular profiling and helps guide treatment decisions, which can lead to improved outcomes and a better overall patient experience.

Asset Subtitle

Lucy Corke

Meta Tag

Speaker Lucy Corke

Topic Global Health, Health Services Research, and Health Economics - Support to Patients and Staff

Keywords

liquid biopsy

quality of life

non-small cell lung cancer

NSCLC

plasma cell-free DNA

molecular profiling

tissue biopsies

targeted therapy

immunotherapy

chemotherapy