2022 World Conference on Lung Cancer (ePosters)-EP07.01-015. Multimodality Imaging for Characterization, Classification, and Staging of Malignant Pleural Mesothelioma, Focusing on MR Imaging

EP07.01-015. Multimodality Imaging for Characterization, Classification, and Staging of Malignant Pleural Mesothelioma, Focusing on MR Imaging

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A study conducted in South Korea aimed to evaluate the role of multimodality imaging in patients with malignant pleural mesothelioma (MPM) who underwent upfront surgery. MPM is a rare and aggressive malignancy associated with a poor prognosis, often caused by asbestos exposure. The study included 26 patients who underwent surgery for curative intent and underwent preoperative CT, MRI, and/or PET/CT scans.<br /><br />The results showed that MRI was more sensitive and accurate than CT for evaluating the invasion of the diaphragm and chest wall. The diagnostic accuracy of nodal stage was 69.2% with low sensitivity but high specificity using MRI. The presence of pleural mass or nodule, maximum pleural thickness on MRI and CT, and pericardial invasion with epicardial fat involvement on MRI were identified as prognostic risk factors.<br /><br />The study also found that the median disease-free survival was 9.9 months and the median overall survival was 20.6 months. The recurrence rate was 73.1%, with locoregional recurrence being the most common type.<br /><br />No findings suggestive of asbestosis or asbestos-related pleural disease were detected in any of the patients.<br /><br />In conclusion, multimodality imaging, especially MRI, can play a valuable role in the preoperative evaluation of patients with MPM. It can help in better selecting patients for surgery by assessing the anatomical details and tumor burden. The identified prognostic risk factors can aid in predicting disease recurrence and survival outcomes. Further research and larger studies are needed to confirm these findings and establish guidelines for the management of MPM.

Asset Subtitle

Mi young Kim

Meta Tag

Speaker Mi young Kim

Topic Mesothelioma, Thymoma, and Other Thoracic Malignancies - Clinical

Keywords

multimodality imaging

malignant pleural mesothelioma

MRI

PET/CT scans

prognostic risk factors

disease-free survival

recurrence rate

preoperative evaluation

tumor burden