2022 World Conference on Lung Cancer (ePosters)-EP13.01-006. Safety of Image Guided Research Biopsies in Patients with Thoracic Malignancies

Pdf Summary

The study evaluated the safety of image-guided research biopsies in patients with thoracic malignancies. The researchers compared the adverse events (AE) between patients who underwent biopsies for research purposes (RO) and those who had biopsies for clinical indications (CICT). They also assessed the risk of complications in lung biopsies and analyzed the impact of pleural distance on adverse events.<br /><br />The results showed that the frequency of adverse events was similar between the RO and CICT groups, both in unadjusted and adjusted analyses. Lung biopsies had a higher risk of adverse events compared to non-lung biopsies. However, the risk was associated with lesion characteristics rather than patient characteristics. The study suggested that multidisciplinary communication between researchers and interventional radiologists could reduce the risk of adverse events in lung biopsies.<br /><br />The study also analyzed the distribution of biopsy sites and the number of cores collected in patients with thoracic cancers. Lung and liver were the most commonly sampled organs. Additionally, the study examined the needle gauge used for liver and lung targets and provided information on the final pathology of the biopsies.<br /><br />The researchers compared the adverse events in lung biopsies between the RO and CICT groups. The results showed that the risk of adverse events was higher in the RO group compared to the CICT group. Representative CT images demonstrated the complications associated with lung biopsies, such as pneumothorax.<br /><br />In conclusion, the study found that image-guided research biopsies in patients with thoracic malignancies have a similar safety profile to biopsies performed for clinical indications. The risk of adverse events was higher in lung biopsies compared to non-lung biopsies, but this was attributed to lesion characteristics rather than patient characteristics. Multidisciplinary communication and careful patient and lesion selection were suggested to reduce the risk of adverse events in lung biopsies.

Asset Subtitle

Jia Luo

Meta Tag

Speaker Jia Luo

Topic Pulmonology, Radiology, and Staging

Keywords

image-guided research biopsies

safety evaluation

thoracic malignancies

adverse events

research purposes

clinical indications

lung biopsies

pleural distance

complications

multidisciplinary communication