2022 World Conference on Lung Cancer (ePosters)-EP13.01-008. Needle Aspiration versus Forceps Biopsy Using Electromagnetic Navigation Bronchoscopy: CONFIDENT-ENB Trial Design

EP13.01-008. Needle Aspiration versus Forceps Biopsy Using Electromagnetic Navigation Bronchoscopy: CONFIDENT-ENB Trial Design

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This document outlines the design of the CONFIDENT-ENB trial, which aims to compare the diagnostic performance of needle aspiration and forceps biopsy using electromagnetic navigation bronchoscopy (ENB) for diagnosing peripheral lung lesions. ENB is an advanced imaging-guided bronchoscopy technique. The trial will investigate whether combining ENB-guided needle aspiration and forceps biopsy provides synergistic benefits in terms of diagnostic yield. The study will recruit 142 participants with lung lesions suspected of malignancy who will undergo ENB procedures. Participants will undergo needle aspiration and forceps biopsy in a randomized order and will be followed up for up to 12 months to determine the final diagnosis of the biopsied lesions. The primary endpoint is the diagnostic performance of ENB-guided needle biopsy and forceps biopsy, as well as the yield achieved by combining the two modalities. The study aims to provide insights into the optimal tool-selection strategy and to improve understanding of the differences between needle aspiration and forceps biopsy. The findings of this trial will inform future comparative studies in the field of guided bronchoscopy for diagnosing lung lesions.

Asset Subtitle

Yeon Wook Kim

Meta Tag

Speaker Yeon Wook Kim

Topic Pulmonology, Radiology, and Staging

Keywords

CONFIDENT-ENB trial

needle aspiration

forceps biopsy

electromagnetic navigation bronchoscopy

diagnostic performance

peripheral lung lesions

advanced imaging-guided bronchoscopy technique

synergistic benefits

diagnostic yield

142 participants