2022 World Conference on Lung Cancer (ePosters)-EP13.01-012. Exploring Factors Affecting Variability in Lung Cancer Outcomes Across Southeastern Ontario, Canada

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A study was conducted to explore the factors affecting lung cancer outcomes in Southeastern Ontario, Canada. Lung cancer is the leading cause of cancer-related mortality, and the five-year survival rate in the region was found to be 22%. The study focused on the Lung Diagnostic Assessment Program (LDAP), a clinic that provides efficient and guideline-recommended care to patients undergoing evaluation for suspected lung cancer.<br /><br />The researchers conducted a population-based retrospective cohort study using data from the LDAP database from January 2017 to December 2019. They linked this data to the Ontario Cancer Registry to identify patients with newly diagnosed lung cancer. The study compared the two-year survival rates of patients receiving care through the LDAP pathway versus non-LDAP pathways using a Cox-model approach.<br /><br />The analysis included a total of 1,741 patients with lung cancer, of which 47% were managed through the LDAP pathway and 53% through non-LDAP pathways. The results showed that LDAP management remained a significant factor influencing two-year survival even after adjusting for other variables. Factors associated with a lower probability of dying at two years included younger age, female sex, shorter distance from the cancer center, and earlier stage. On the other hand, lower income quintile, non-adenocarcinoma subtype, and non-LDAP management were associated with a higher probability of dying.<br /><br />Patient and disease factors associated with LDAP management included ages 61-70, higher income quintile, and earlier stage. Increasing distance from the cancer center lowered the probability of LDAP assessment. The study concluded that while several patient and disease factors influence lung cancer survival in Southeastern Ontario, the management provided by the LDAP appears to be an independent factor influencing survival, highlighting the role of system characteristics in patient outcomes.<br /><br />Further research may be warranted to better understand the impact of system factors on lung cancer outcomes and to identify strategies to improve survival rates in this region.

Asset Subtitle

Shahad AlGhamdi

Meta Tag

Speaker Shahad AlGhamdi

Topic Pulmonology, Radiology, and Staging

Keywords

lung cancer

Southeastern Ontario

Canada

cancer-related mortality

five-year survival rate

Lung Diagnostic Assessment Program

LDAP

retrospective cohort study

two-year survival rates

Cox-model approach