2023 IASLC CT Screening Workshop-Who Should Be Screened

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Video Summary

The debate centered around the topic of lung cancer screening in never-smokers and the challenges associated with it. The main question was whether never-smokers with certain risk factors should be screened for lung cancer. The debate began with an overview of the effectiveness of low-dose CT screening and its ability to detect early-stage lung cancer, especially in high-risk populations. The Asian perspective was also discussed, highlighting the high prevalence of non-smoking lung cancer in Asia. The debate then shifted to the potential harms of screening, such as overdiagnosis and overtreatment. Studies were presented showing a high detection rate and a high proportion of early-stage lung cancer in non-smokers, raising concerns about overdiagnosis. The cost-effectiveness of screening and the need for individualized strategies were also discussed. Another important point was the need to define risk factors and establish clear criteria for screening. The debate concluded with a call for sharper tools and additional tests to improve screening accuracy, as well as the importance of considering both the person-level and population-level perspectives when making decisions about lung cancer screening.

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Keywords

lung cancer screening

never-smokers

challenges

low-dose CT screening

early-stage lung cancer

overdiagnosis

cost-effectiveness

risk factors