2023 North America Conference on Lung Cancer (NACLC) - Posters and Abstracts-PP01.109 (Poster) Concordance of Breast Density Between Low-Dose CT and Mammogram

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In a study on women with dense breasts, it was found that there was a high level of agreement between low-dose CT (LDCT) and mammography in identifying breast density. However, only 36% of the participants underwent supplemental breast imaging despite having dense breasts. This highlights the need for education and encouragement for women with dense breasts to undergo additional testing. LDCT findings can inform both women and healthcare providers, leading to the recommendation of supplemental testing. As interpreting LDCT for breast density improves, there will likely be fewer discordant results, providing an opportunity for those with dense breasts on LDCT to receive supplemental imaging.<br /><br />The study included 88 participants, and 32 (36%) of them received additional testing. All of those who received additional testing underwent an ultrasound, and only one participant also had an MRI. Of the 88 participants, 60 had a mammogram available, and in 52 cases (87%), the mammographic determination of dense breasts was consistent with the LDCT finding. The remaining 8 cases (13%) were discordant, as their mammograms were interpreted as having scattered areas of fibroglandular density, but further review confirmed that they were not dense.<br /><br />The participants were classified into four breast density categories: fatty, scattered, heterogeneously dense, and extremely dense. However, no participants fell into the fatty or scattered categories due to the exclusion criteria of the study. 80 participants were characterized as heterogeneously dense, and 8 participants were extremely dense.<br /><br />Out of the 52 concordant cases, only 17 (32.7%) received supplemental imaging after the initial scan, while only one participant out of the eight discordant cases (12.5%) received supplemental imaging. Further analysis of the discordant cases is needed to understand why there was a low rate of supplemental imaging in these cases.<br /><br />Overall, this study highlights the importance of additional testing in women with dense breasts, as identified by LDCT. The findings emphasize the need to educate and encourage women with dense breasts to undergo supplemental imaging in addition to mammography.

Asset Subtitle

L.J. Lentini

Keywords

women with dense breasts

low-dose CT

mammography

breast density

supplemental breast imaging

education

encouragement

ultrasound

MRI

breast density categories