2023 North America Conference on Lung Cancer (NACLC) - Posters and Abstracts-PP01.137 Priyanka Reddy NACLC23 Abstract

PP01.137 Priyanka Reddy NACLC23 Abstract

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This study focused on the survival outcomes of early-stage non-small cell lung cancer (NSCLC) patients at a safety-net hospital in North Texas, as well as the impact of low-dose CT scan (LDCT) screening. The researchers conducted a retrospective study on patients diagnosed with early-stage NSCLC at the hospital from 2013 to 2021. They collected data on demographics, treatment, and LDCT status from the hospital's tumor registry and electronic medical records. The overall survival probability was modeled using a Kaplan-Meier curve, and log-rank tests were used to compare survival distribution across patient characteristics.<br /><br />The analysis included 123 patients, with 104 in stage 1 and 19 in stage 0. The main treatments were surgery (55%) and radiation (19%), while 26% of patients did not receive treatment. Of the deceased patients, most died from NSCLC, but some died from a different cancer or other causes. The overall survival at one year was 84% and at five years was 46%. Female and Asian patients had better survival rates. Surgery resulted in a higher survival rate compared to radiation.<br /><br />The researchers also noted the utilization of LDCT screening, with 20 early-stage cancers diagnosed through this method. These cases showed higher survival probabilities, but the difference did not reach statistical significance.<br /><br />In conclusion, patients treated with surgery for early-stage NSCLC at this safety-net hospital had comparable survival rates to those reported in the Surveillance, Epidemiology, and End Results (SEER) database. LDCT screening was widely used, but a significant proportion of patients did not receive treatment, potentially due to socioeconomic factors and comorbidities common in the safety-net hospital population.

Keywords

non-small cell lung cancer

NSCLC

survival outcomes

safety-net hospital

North Texas

low-dose CT scan

LDCT screening

retrospective study

Kaplan-Meier curve

log-rank tests