2023 North America Conference on Lung Cancer (NACLC) - Posters and Abstracts-PP01.41 (Poster) Clinical Trial Enrollment Success of Underrepresented Patients with Lung Cancer at a Single Institution

PP01.41 (Poster) Clinical Trial Enrollment Success of Underrepresented Patients with Lung Cancer at a Single Institution

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Clinical trial enrollment for cancer patients is typically low, with only around 8% of patients enrolling nationwide. Additionally, minority groups are severely underrepresented, with around 90% of enrolled patients identifying as White. This lack of representation is problematic because advancements in scientific research should benefit everyone. However, a recent study conducted at the Thoracic Oncology Clinic (TOC) at UI Health demonstrated significant success in clinical trial enrollment, with a 26% participation rate among eligible patients. This rate exceeds the national average and highlights the efficacy of strategies implemented at UI Health.<br /><br />Notably, the TOC at UI Health also excelled in enrolling underrepresented minorities, with a substantial 60% of Black individuals participating in clinical trials, which exceeds the national average of 5-8%. The study identified barriers to enrollment, such as medical criteria disqualifications (11%) and patient declinations (30%), providing valuable insights for future interventions.<br /><br />The success of the TOC at UI Health in clinical trial enrollment holds implications for addressing disparities in participation. It serves as a model for achieving more equitable representation, aligning with national goals to improve diversity in clinical trials. Moreover, the clinic's patient-centered approach, emphasizing access to trials, demonstrates a commitment to advancing the understanding and treatment of lung cancer for a diverse patient demographic.<br /><br />These findings pave the way for further research to understand the factors contributing to high enrollment rates at UI Health. This knowledge can be leveraged to develop tools and strategies that can be implemented at other healthcare sites, thereby improving clinical trial participation on a broader scale. Ultimately, the success at UI Health promises improved clinical outcomes for a diverse patient population and offers guidance for a more inclusive approach to clinical trial recruitment nationwide.

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Chris Zazueta

Keywords

clinical trial enrollment

underrepresented minorities

Thoracic Oncology Clinic

UI Health

enrollment rate

barriers to enrollment

equitable representation

patient-centered approach

high enrollment rates

clinical trial recruitment