2023 North America Conference on Lung Cancer (NACLC) - Posters and Abstracts-PP01.60 (Poster) Nodify Lung Risk Assessment Testing in Deciphering the Risk of Malignancy of a Lung Nodule

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A study was conducted to evaluate the use of the Nodify Lung Test in assessing the risk of malignancy in lung nodules among first responders. The study included 40 first responders, with an average age of 49, who underwent the Nodify Lung Test. None of the patients had a history of cancer, and all of them were non-smokers.<br /><br />The results showed that the Nodify Lung Test was beneficial in determining the risk of malignancy in lung nodules and reclassified 27.5% of the nodules. It was able to differentiate between benign and malignant nodules, improve patient compliance, reduce the need for further CT scans, and alleviate patient anxiety and stress during the follow-up period. The test was well received by the first responders and will continue to be used in the program.<br /><br />The Nodify Lung Test combines dynamic proteomic insights with clinical risk assessment to provide an individualized risk of malignancy for lung nodules. It is used in patients aged 40 and above with non-calcified nodules 8mm and larger.<br /><br />Currently, the standard of care for new lung nodules relies on radiological features and the patient's medical history to inform further diagnosis. However, nearly 75% of patients have low to moderate risk nodules, creating uncertainty about the next steps. The Nodify Lung Test aims to provide a more personalized risk assessment to support shared decision making.<br /><br />First responders, such as firefighters and police officers, are at a high risk of developing lung cancer due to occupational exposure. This study evaluated the integration of the Nodify Lung Test in assessing the risk of malignancy in lung nodules among this high-risk group.<br /><br />Overall, the study suggests that the Nodify Lung Test is a valuable tool in assessing the risk of malignancy in lung nodules, especially among high-risk individuals like first responders. It provides more accurate risk assessment and can help guide treatment decisions and surveillance strategies.

Asset Subtitle

Vershalee Shukla

Keywords

Nodify Lung Test

malignancy risk assessment

lung nodules

first responders

radiological features

dynamic proteomic insights

benign and malignant nodules

patient compliance

CT scans

personalized risk assessment