2023 North America Conference on Lung Cancer (NACLC) - Posters and Abstracts-PP01.64 (Poster) Disparities in the impact of advances in metastatic non-small cell lung cancer therapy on mortality in the United States

PP01.64 (Poster) Disparities in the impact of advances in metastatic non-small cell lung cancer therapy on mortality in the United States

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This study examines the impact of advances in therapy for metastatic non-small cell lung cancer (NSCLC) on mortality rates in the United States. NSCLC accounts for the majority of lung cancer cases in the US, and metastatic disease is associated with poor survival. The use of immunotherapy and targeted therapy for lung cancer has increased in recent years, leading to improved survival for some patients. However, it is unclear if these advancements have benefited all patients equally or if disparities in survival rates still exist.<br /><br />The researchers analyzed data from the Surveillance, Epidemiology, and End Results (SEER) database between 2004 and 2019. They compared survival trends based on sex, race/ethnicity, and residence type (urban or rural). The results showed that overall survival rates for metastatic NSCLC improved over the study period for both men and women. Women had higher survival rates compared to men, but the trends were similar.<br /><br />When analyzing by race, Black patients experienced a relatively rapid improvement in survival, while White patients had a gradual increase followed by a more rapid increase in survival. Despite these differences, the survival gap between Blacks and Whites narrowed over time.<br /><br />Urban dwellers had higher survival rates and experienced a more rapid acceleration in survival compared to rural dwellers. The gap in survival between urban and rural dwellers widened over the study period.<br /><br />The study concludes that while survival rates have improved for all patients, there are still disparities in survival based on race and residence. Furthermore, the survival gap between men and women persists. The researchers emphasize the need for innovative care delivery models to bridge the gap in oncology services and improve survival rates for metastatic NSCLC patients.

Asset Subtitle

Akanbi Maxwell

Keywords

advances in therapy

metastatic non-small cell lung cancer

mortality rates

United States

immunotherapy

targeted therapy

survival rates

disparities in survival

SEER database

race/ethnicity