2023 Radiation Oncology Update-2023 Radiation Oncology Update

Video Transcription

Video Summary

IASLC hosted a webinar titled "2023 Radiation Oncology Updates" which covered recent research and updates in the field of radiation oncology. The webinar included presentations and discussions on various topics such as early-stage non-small cell lung cancer, locally advanced lung cancer, and oligometastatic cancers. <br /><br />One of the topics discussed was the role of immunotherapy in early-stage non-small cell lung cancer. The results of the iSABR trial, a phase 2 randomized trial, showed that patients who received SABR with immunotherapy had a significantly increased event-free survival compared to those who received SABR alone. However, there were some immunological adverse events related to the use of immunotherapy. The study concluded that while it is a promising approach, further research is needed to fully understand the efficacy and safety of this treatment combination. <br /><br />Another topic discussed was the use of stereotactic radiotherapy (SBRT) in oligoprogressive disease. The STOP trial showed that SBRT, in combination with systemic anti-cancer therapy, resulted in improved progression-free survival compared to systemic therapy alone in patients with limited disease progression. However, the study also highlighted the need for larger studies to further evaluate the role of SBRT in oligoprogressive disease. <br /><br />In the context of locally advanced lung cancer, the webinar discussed the importance of cardiac toxicity and the need for strict cardiac constraints to reduce the risk of cardiac events. The studies presented showed that patients who received radiation treatment with lower cardiac doses had better outcomes in terms of lymphopenia and survival. The webinar also emphasized the importance of systematic mediastinal staging using endobronchial ultrasound (EBUS) to accurately assess lymph node involvement and guide treatment planning. <br /><br />Overall, the webinar provided valuable updates on the use of radiation therapy in lung cancer treatment and highlighted the need for further research to improve outcomes and reduce toxicity in patients.

Keywords

IASLC

webinar

Radiation Oncology Updates

immunotherapy

SABR

adverse events

SBRT

oligoprogressive disease

cardiac toxicity

lung cancer treatment