2023 World Conference on Lung Cancer (Posters)-EP01.01. Casual Effects of Some Chronic Respiratory Diseases on Squamous Cell Lung Cancer: A Mendelian Randomization Study

EP01.01. Casual Effects of Some Chronic Respiratory Diseases on Squamous Cell Lung Cancer: A Mendelian Randomization Study - PDF(Slides)

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A new study has used mendelian randomization (MR) analysis to investigate the causal relationship between chronic respiratory diseases and squamous cell lung cancer. The study found that there is a causal relationship between chronic obstructive pulmonary disease (COPD) and squamous cell lung cancer. However, the study did not find a causal relationship between asthma, obstructive sleep apnea (OSA), and bronchiectasis with squamous cell lung cancer. In addition, the study also found a positive association between idiopathic pulmonary fibrosis (IPF) and squamous cell lung cancer, but this association was not significant after adjusting for smoking and exposure to tobacco. The study suggests that COPD and IPF are independent risk factors for the development of squamous cell lung cancer. However, more research is needed to further explore the interactions between these respiratory diseases and lung cancer.

Asset Subtitle

Xiaoxue Cheng

Meta Tag

Speaker Xiaoxue Cheng

Topic Risk Factors, Risk Reduction & Tobacco Control

Keywords

mendelian randomization

chronic respiratory diseases

squamous cell lung cancer

COPD

asthma

obstructive sleep apnea

bronchiectasis

idiopathic pulmonary fibrosis

independent risk factors

interactions