2023 World Conference on Lung Cancer (Posters)-EP01.01. Gender and Lung Cancer (LC): Preliminary Data from a Prospective, Woman-Centered Local Registry

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This document is a summary of a presentation titled "Gender and Lung Cancer: Preliminary Data from a Prospective, Woman-Centered Local Registry" at the WCLC 2023 conference. The presentation aimed to explore the impact of gender on the incidence, susceptibility, and severity of lung cancer (LC), particularly in South American women.<br /><br />The study included a cohort of 100 women diagnosed with LC at a public referral Cancer Center. The women participated in a female-specific epidemiological interview, where data on sociodemographic characteristics, reproductive factors, hormonal therapy, lifestyle, occupational exposure, personal and family history of LC, molecular markers, treatment access, and disease outcome were collected.<br /><br />From the interviews, it was found that the majority of women in the cohort were postmenopausal, had children, and had completed basic education. While a significant percentage of women in the cohort were never smokers, a high proportion (69%) were exposed to passive smoking, mainly in their homes. A substantial number of women (42%) reported exposure to potential occupational or environmental carcinogens.<br /><br />The most common histological subtype of LC observed in the cohort was adenocarcinoma (80%), and 40% of women presented with stage IV LC. Approximately 28% of the women had a history of another cancer, with breast cancer being the most common type. Additionally, a significant proportion of women had a family history of LC in first-degree relatives (33%).<br /><br />Overall, the preliminary analysis suggests that tobacco exposure remains the main risk factor for the development of LC in this population of women. However, hormonal factors and potential occupational or environmental local carcinogens should also be explored further. The findings highlight the importance of including women with a previous breast cancer diagnosis in LC screening programs, as LC was detected in their breast imaging controls.<br /><br />In conclusion, further research is needed to understand the specific risk factors and characteristics of LC in South American women, taking into account factors such as tobacco exposure, occupational and environmental carcinogens, and family history.

Asset Subtitle

Mónica Castro

Meta Tag

Speaker Mónica Castro

Topic Risk Factors, Risk Reduction & Tobacco Control

Keywords

Gender

Lung Cancer

South American women

incidence

sociodemographic characteristics

occupational exposure

family history

adenocarcinoma

tobacco exposure

risk factors