2023 World Conference on Lung Cancer (Posters)-EP01.01. Long-term Survivals Associated with High Levels of Na+ and Ca2+ in the Blood of Patients with Stage IV Lung Cancer

EP01.01. Long-term Survivals Associated with High Levels of Na+ and Ca2+ in the Blood of Patients with Stage IV Lung Cancer - PDF(Abstract)

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A study presented at the WCLC 2023 conference focused on the correlation between blood ion levels and survival in patients with stage IV lung cancer. The study aimed to explore the association between pre-treatment blood ion concentrations and survival, the relationship between blood ion levels and blood cell types, and the connection between blood ion levels and liver-kidney function. <br /><br />The study included 112 stage IV lung cancer patients, with 75 patients having a minimum follow-up of 1 year. The cohort consisted of 67 males and 45 females, ranging in age from 34 to 89 years. The 1-year survival rate for patients was 67%. <br /><br />The results showed a significant correlation between the levels of sodium (Na) and calcium (Ca2) in the blood and overall survival. Cox regression models demonstrated that higher levels of Na and Ca2 were associated with better survival outcomes. On the other hand, potassium (K) levels did not show a significant correlation with survival. <br /><br />The study also found a strong correlation between Na levels and lymphocyte percentage, red blood cell count, neutrophil percentage, and platelet count. Patients with higher levels of Na had higher lymphocyte levels. However, there was no significant correlation between Na levels and liver-kidney function measures. <br /><br />The study concluded that the levels of Na and Ca2 in the blood may affect the survival of patients with stage IV lung cancer. Attention should be paid to electrolyte levels, and their correction may potentially improve treatment outcomes in lung cancer patients. The underlying mechanism behind these correlations is not yet known and requires further research.

Asset Subtitle

Feng-Ming (Spring) Kong

Meta Tag

Speaker Feng-Ming (Spring) Kong

Topic Risk Factors, Risk Reduction & Tobacco Control

Keywords

blood ion levels

survival

stage IV lung cancer

pre-treatment

blood ion concentrations

blood cell types

liver-kidney function

sodium

calcium

potassium