2023 World Conference on Lung Cancer (Posters)-EP01.01. Long-term Survivals Associated with High Levels of Na+ and Ca2+ in the Blood of Patients with Stage IV Lung Cancer

EP01.01. Long-term Survivals Associated with High Levels of Na+ and Ca2+ in the Blood of Patients with Stage IV Lung Cancer - PDF(Slides)

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A study conducted at The University of Hong Kong Shenzhen Hospital and The University of Hong Kong aimed to investigate the relationship between electrolyte levels in the blood and the survival of patients with stage IV lung cancer. The researchers hypothesized that electrolytes play a significant role in maintaining the stability of the cell environment and the functioning of tissues and organs, thus affecting survival.<br /><br />The retrospective study included 75 patients with stage IV lung cancer who received treatment at HKU SZH. The patients had a minimum follow-up of one year and underwent complete blood tests, including counts of lymphocytes. The levels of sodium (Na), calcium (Ca2), and potassium (K) in the blood were also measured.<br /><br />The results showed that there were significant correlations between the levels of Na and Ca2 and survival, while there was no significant correlation between K and survival. Patients with low levels of Na and Ca2 had lower levels of lymphocytes. Additionally, the levels of Na were strongly correlated with lymphocyte, red blood cell, neutrophil, and platelet counts.<br /><br />Based on these findings, the study suggests that the circulating levels of Na and Ca2 have a significant impact on the overall survival of patients with stage IV lung cancer. The authors recommend paying attention to electrolyte levels in patients with lung cancer and timely correction if necessary, as it may improve treatment outcomes. Further research is needed to understand the underlying mechanism of Na and Ca2 on survival and explore the correlation with lymphocytes.<br /><br />The study was supported by the Shenzhen Science and Technology Program Grant. A validation study including 201 patients receiving radiation therapy is ongoing, with results expected in the near future. The researchers acknowledge the physicians involved in patient care and the research team members who contributed to data collection.

Asset Subtitle

Feng-Ming (Spring) Kong

Meta Tag

Speaker Feng-Ming (Spring) Kong

Topic Risk Factors, Risk Reduction & Tobacco Control

Keywords

University of Hong Kong Shenzhen Hospital

electrolyte levels

blood

survival

stage IV lung cancer

lymphocytes

sodium

calcium

correlations

treatment outcomes