2023 World Conference on Lung Cancer (Posters)-EP01.01. Postoperative Course of Surgically Resected Lung Cancer Patients in Preserved Ratio Impaired Spirometry

EP01.01. Postoperative Course of Surgically Resected Lung Cancer Patients in Preserved Ratio Impaired Spirometry - PDF(Abstract)

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This study examined the postoperative course of lung cancer patients with preserved ratio impaired spirometry (PRISm). PRISm is a condition characterized by reduced FEV1 and FVC, but with a normal FEV1/FVC ratio. The purpose of the study was to evaluate postoperative complications and survival for lung cancer patients with PRISm. The medical records of 1807 patients who underwent lung cancer surgery at the Shizuoka Cancer Center were reviewed. Patients were classified into different lung function categories, including normal spirometry, PRISm, and airflow limitation (AFL) based on the Global Initiative for Chronic Obstructive Lung Disease guidelines. The occurrence of postoperative complications within 30 days after surgery was assessed, and survival rates were analyzed based on lung function categories and smoking status. The results showed that postoperative complications were more common in smokers, particularly in patients with chronic obstructive pulmonary disease (COPD). However, the occurrence of complications in the PRISm group was not significantly different from the normal function group. The overall survival rate for the PRISm group was lower compared to the normal function group, similar to the COPD group. For patients with stage I lung cancer, the PRISm group had a significantly worse prognosis than the normal function group. The study concluded that perioperative intervention may not be necessary for PRISm patients in the short term, as postoperative complications were not common. However, PRISm patients had a poorer long-term prognosis, suggesting that some interventions may improve their survival outcomes. Further research is needed to better understand the impact of PRISm on the postoperative course of lung cancer patients.

Asset Subtitle

Hayato Konno

Meta Tag

Speaker Hayato Konno

Topic Risk Factors, Risk Reduction & Tobacco Control

Keywords

lung cancer

PRISm

spirometry

FEV1

FVC

FEV1/FVC ratio

postoperative complications

survival rates

chronic obstructive pulmonary disease

COPD