2023 World Conference on Lung Cancer (Posters)-EP01.01. Sex Difference Indicate Survival Disparity in Resected NSCLC, from a Large Chinese Cohort

EP01.01. Sex Difference Indicate Survival Disparity in Resected NSCLC, from a Large Chinese Cohort - PDF(Abstract)

Pdf Summary

This study examined the survival disparity between male and female patients with non-small cell lung cancer (NSCLC) in a large Chinese cohort. The researchers analyzed the data of 8,549 patients who underwent R0 lung tumor resection at Zhongshan Hospital, Fudan University from 2007 to 2017. They found that females tended to have longer survival than males after surgery. This survival discrepancy persisted when the patients were divided into subgroups based on histological types, with females having better survival in lung adenocarcinoma but not in lung squamous cell carcinoma. Further analysis revealed that females had inferior survival compared to males in the stage II-IV lung squamous cell carcinoma subgroup. Additionally, the study found that adjuvant chemotherapy had optimal efficacy in males but provided little benefit to females with advanced NSCLC. <br /><br />The findings suggest that the survival disparity between males and females with NSCLC varies depending on the specific histological type and tumor stage. As a result, treatment options should be tailored and examined differently for patients of different genders.

Asset Subtitle

Yifan Guo

Meta Tag

Speaker Yifan Guo

Topic Risk Factors, Risk Reduction & Tobacco Control

Keywords

survival disparity

male

female

NSCLC

Chinese cohort

lung tumor resection

histological types

lung adenocarcinoma

lung squamous cell carcinoma

treatment options