2023 World Conference on Lung Cancer (Posters)-EP06.05. Efficacy of Preoperative Biopsy in Predicting the Newly Proposed Histologic Grade of Resected Lung Adenocarcinoma

EP06.05. Efficacy of Preoperative Biopsy in Predicting the Newly Proposed Histologic Grade of Resected Lung Adenocarcinoma - PDF(Slides)

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A study was conducted to assess the effectiveness of preoperative biopsy in predicting the newly proposed histologic grade of surgically resected lung adenocarcinoma. The study analyzed biopsy specimens and surgically resected samples from 222 patients with invasive lung adenocarcinoma. The newly proposed grading system by the World Health Organization (WHO) was used to classify the specimens.<br /><br />The results showed that the overall concordance rate between preoperative biopsy and surgically resected samples for the novel WHO grades was 81.5%. The concordance rate of grades 1 (well-differentiated) and 3 (poorly differentiated) was higher compared to grade 2 (moderately differentiated). Preoperative biopsy specimens were found to accurately predict the novel WHO grades, indicating the potential for more accurate patient selection for preoperative treatment or sublobar resection.<br /><br />The study suggests that the novel grading system allows for better prediction of histologic grades compared to the former grading system. It highlights the importance of using preoperative biopsy as a tool for determining the appropriate treatment approach for patients with lung adenocarcinoma.<br /><br />In terms of future prospects, the study recommends larger cohort studies using technologies such as robotic bronchoscopy to further verify the accuracy of preoperative biopsy in predicting histologic grades. This can help improve patient selection for treatment and ensure better outcomes for patients with lung adenocarcinoma.<br /><br />Overall, the study demonstrates the efficacy of preoperative biopsy in predicting the histologic grade of surgically resected lung adenocarcinoma. The findings can have implications for treatment decision-making and improve patient outcomes in the management of lung adenocarcinoma.

Asset Subtitle

Seiyu Ohtani

Meta Tag

Speaker Seiyu Ohtani

Topic Pathology & Biomarkers

Keywords

study

preoperative biopsy

effectiveness

histologic grade

surgically resected

lung adenocarcinoma

grading system

World Health Organization

concordance rate

patient selection