2023 World Conference on Lung Cancer (Posters)-EP06.06. Correlation between Vitamin C and CRP Serum Levels in Non Small Cell Lung Cancer Patient Among Sumatera Utara Population

EP06.06. Correlation between Vitamin C and CRP Serum Levels in Non Small Cell Lung Cancer Patient Among Sumatera Utara Population - PDF(Abstract)

Back to course

Pdf Summary

This study aimed to determine the correlation between Vitamin C and C-reactive protein (CRP) serum levels in non-small cell lung cancer (NSCLC) patients among the population of Sumatera Utara. NSCLC is a leading cause of cancer-related deaths, and the growth and metastasis of lung cancer cells can disrupt normal tissue integrity and trigger an inflammatory response. CRP, produced by the liver, is known as a marker of ongoing inflammation, including malignancy.<br /><br />Vitamin C, a water-soluble micronutrient, can be obtained through food and supplements, and previous studies have suggested the susceptibility of cancer cells, especially to high doses of Vitamin C. This observational study analyzed data from NSCLC patients in Sumatera Utara between January and April 2023, using cross-sectional methods. A total of 53 patients diagnosed with NSCLC were included in the study, and serum levels of Vitamin C and CRP were measured using a single blood sample.<br /><br />The results showed that all patients in the study had a Vitamin C deficiency, with values ranging from 0.05mg/dL to 0.0001mg/dL. Additionally, 90.6% of patients had high CRP values, ranging from 7mg/dL to 0.3mg/dL. The data distribution of Vitamin C and CRP values was not normally distributed. The correlation test revealed a very weak, non-significant positive correlation (r=0.078, p>0.05) between CRP and Vitamin C serum levels in NSCLC patients.<br /><br />In conclusion, this study found no significant correlation between Vitamin C and CRP serum levels in NSCLC patients among the population of Sumatera Utara. This research provides valuable information about the relationship between these biomarkers in the context of lung cancer, contributing to the understanding of the disease and its potential diagnostic and prognostic markers. However, further research is needed to validate these findings and explore other potential biomarkers for NSCLC.

Asset Subtitle

Elizabeth Napitupulu

Meta Tag

Speaker Elizabeth Napitupulu

Topic Pathology & Biomarkers: Prognostic Biomarkers

Keywords

correlation

Vitamin C

C-reactive protein

CRP

serum levels

non-small cell lung cancer

NSCLC patients

Sumatera Utara

biomarkers

diagnostic markers