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2023 World Conference on Lung Cancer (Posters)
EP07.01. Comparison of Surveillance with Contrast ...
EP07.01. Comparison of Surveillance with Contrast Chest CT and Non-contrast Chest CT among who Survived 2 Years after Curative Resection for Lung Cancer - PDF(Abstract)
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This study aimed to compare the use of non-contrast chest CT (NCCT) versus contrast chest CT (CCT) for surveillance in patients who survived 2 years after curative resection for lung cancer. The researchers analyzed data from 1995 patients who underwent curative resection from January 2011 to June 2017. Patients were excluded if they had recurrence or follow-up loss, multiple lung cancer operations, absence of CT follow-up, renal insufficiency, or contrast allergy.<br /><br />The primary endpoint of the study was overall survival (OS) and the secondary endpoint was recurrence-free survival (RFS) comparing the two groups. The results showed that the 5-year survival rate from the time of surgery was significantly different between the NCCT and CCT groups for RFS (98.2% for NCCT vs 93.5% for CCT) but not for OS (98.2% for NCCT vs 96.8% for CCT). Subgroup analysis based on pathologic stage showed similar findings, with RFS being significantly different between the two groups for stage I (98.7% for NCCT vs 96.0% for CCT) and stage II (93.8% for NCCT vs 86.6% for CCT) patients.<br /><br />The study concluded that NCCT detected recurrence later than CCT, but the delay in detection did not impact overall survival. This finding was consistent among stage I and stage II patients. The study also provided demographic data on the study population, including age, gender, histology, resection extent, and pathological stage.<br /><br />In summary, this study compared the use of NCCT and CCT for surveillance in patients who survived 2 years after curative resection for lung cancer. The results showed that NCCT detected recurrence later than CCT, but this did not affect overall survival. The study provides valuable insights into best practices for surveillance in early-stage non-small cell lung cancer.
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Topic
Early-Stage NSCLC: Best Practice
Keywords
non-contrast chest CT
contrast chest CT
surveillance
curative resection
lung cancer
overall survival
recurrence-free survival
pathologic stage
delay in detection
early-stage non-small cell lung cancer
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