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2023 World Conference on Lung Cancer (Posters)
EP07.01. Is Chemical Venous Thromboembolism Prophy ...
EP07.01. Is Chemical Venous Thromboembolism Prophylaxis Necessary After Lung Cancer Resection? A 10-year T-ERAS Experience - PDF(Abstract)
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This study aimed to investigate the necessity of chemical prophylaxis for venous thromboembolism (VTE) after lung cancer resection. The 10-year T-ERAS (Thoracic-Enhanced Recovery with Ambulation after Surgery) protocol was implemented at a large academic medical center. The protocol utilized only intra-operative sequential compression devices and early ambulation in the post-anesthesia care unit for VTE prophylaxis. <br /><br />Retrospective data on resections from 2012 to 2022 were analyzed, including demographic information, medical history, comorbidities, antiplatelet use, tumor staging and treatment, surgical characteristics, ambulation data, morbidity, and mortality. The risk for VTE was assessed using the Caprini Risk Assessment Model. <br /><br />The overall cohort consisted of 903 patients with a median age of 68 years. The majority were female (59.4%) and Caucasian (73.6%). Most patients were at high risk for VTE. The incidence of postoperative VTE at 30 days was 0.5%, with no significant associations with the stage of cancer or Caprini-RAM risk category. <br /><br />The study found that implementing the T-ERAS program, which focused on early ambulation, resulted in a low VTE rate despite the absence of chemical prophylaxis. The success of the program was attributed to a standardized early ambulation pathway and a multidisciplinary team. This challenges the current practice of using perioperative chemical prophylaxis for high-risk postoperative lung cancer patients. <br /><br />The authors suggest additional research to explore the benefits of an early ambulation program in improving outcomes for lung cancer patients.
Asset Subtitle
Ju Ae Park
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Speaker
Ju Ae Park
Topic
Early-Stage NSCLC: Best Practice
Keywords
chemical prophylaxis
venous thromboembolism
lung cancer resection
T-ERAS protocol
sequential compression devices
early ambulation
post-anesthesia care unit
Caprini Risk Assessment Model
postoperative VTE
perioperative chemical prophylaxis
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