2023 World Conference on Lung Cancer (Posters)-EP07.01. Predictors of Poor Quality of Life Following Lung Cancer Surgery

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This abstract discusses a study conducted to identify predictors of poor quality of life following lung cancer surgery for stage I-IIIa non-small cell lung cancer (NSCLC). The study was carried out at a high volume thoracic surgical center over the course of a year. Quality of life was assessed using the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 and Lung cancer module LC29 tools at multiple time points pre- and post-operatively.<br /><br />The results showed that obstructive sleep apnea (OSA) was a significant predictor of poor quality of life in the global domain. Education level, tumor size, and forced vital capacity (FVC) were associated with a faster recovery in the global domain. In the physical domain, advanced tumor staging (Stage I vs I-IIIa) was the only statistically significant predictor of poor quality of life. OSA, chronic obstructive pulmonary disease (COPD), diffusing capacity of the lungs for carbon monoxide (DLCO), and FVC were associated with poorer recovery in the physical domain at all time points. OSA also had a significant impact on poor recovery in the cognitive domain. FEV1 and FVC values were correlated with worse recoveries in the cognitive domain.<br /><br />The study concluded that sleep apnea was a common factor affecting quality of life recovery in multiple domains. Additionally, FVC values showed a stronger correlation with quality of life outcomes compared to FEV1. The authors emphasize the importance of understanding predictors of poor quality of life and conducting further research to inform postoperative recovery outcomes in lung cancer surgery patients.<br /><br />Keywords: Lung Cancer, Quality of Life, Thoracic Surgery

Asset Subtitle

Anna McGuire

Meta Tag

Speaker Anna McGuire

Topic Early-Stage NSCLC: Best Practice

Keywords

Lung Cancer

Quality of Life

Thoracic Surgery

Predictors

Obstructive Sleep Apnea

Tumor Size

Forced Vital Capacity

Physical Domain

Cognitive Domain

Postoperative Recovery