2023 World Conference on Lung Cancer (Posters)-EP07.01. Preoperative Respiratory Assessment Predicts Post-Operative Survival in Stage IA Non-small Cell Lung Cancer

EP07.01. Preoperative Respiratory Assessment Predicts Post-Operative Survival in Stage IA Non-small Cell Lung Cancer - PDF(Slides)

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A study conducted at the National Hospital Organization Iwakuni Clinical Center in Japan examined the relationship between preoperative respiratory function and postoperative survival in patients with stage IA non-small cell lung cancer (NSCLC) undergoing pulmonary resection. The study aimed to determine whether preoperative respiratory assessment could predict post-operative recurrence-free survival (RFS) and overall survival (OS).<br /><br />The study included 192 patients with stage IA NSCLC who underwent lung resection between 2012 and 2015. The patients were categorized into three groups based on their preoperative respiratory function: normal respiratory function, obstructive ventilatory impairment (OVI), and restrictive ventilatory impairment (RVI). The study found that patients with RVI had a significantly higher risk of recurrence and shorter survival times compared to those without RVI.<br /><br />The study also assessed the impact of different surgical techniques on survival rates. The results showed that neither RFS nor OS was significantly affected by the surgical technique. However, sublobar resection, such as segmentectomy or wedge resection, trended toward worse RFS and OS in patients with RVI.<br /><br />The study concluded that preoperative restrictive ventilatory impairment could be a poor prognostic factor in patients with stage IA lung cancer undergoing pulmonary resection. The findings suggest that in cases where lobectomy is not feasible due to RVI, careful consideration should be given to whether surgery is indicated. It also emphasized the importance of postoperative respiratory function assessment and monitoring, as respiratory impairment may be a factor for poor prognosis.<br /><br />Overall, the study highlights the significance of preoperative respiratory assessment in predicting post-operative survival outcomes in patients with stage IA NSCLC. By identifying patients with restrictive ventilatory impairment, healthcare professionals can make more informed decisions regarding surgical interventions and postoperative care.

Asset Subtitle

Mototsugu Watanabe

Meta Tag

Speaker Mototsugu Watanabe

Topic Early-Stage NSCLC: Best Practice

Keywords

National Hospital Organization Iwakuni Clinical Center

Japan

preoperative respiratory function

postoperative survival

stage IA non-small cell lung cancer

pulmonary resection

recurrence-free survival

overall survival

obstructive ventilatory impairment

restrictive ventilatory impairment