2023 World Conference on Lung Cancer (Posters)-EP07.02. Image-Guided Thermal Ablation of Early-Stage Non-small Cell Lung Cancer; Five-Year Outcome

EP07.02. Image-Guided Thermal Ablation of Early-Stage Non-small Cell Lung Cancer; Five-Year Outcome - PDF(Abstract)

Pdf Summary

This study focused on assessing the long-term outcomes of medically inoperable patients with stage 1 non-small cell lung cancer (NSCLC) who underwent image-guided thermal ablation. The study included 19 patients with single or multiple stage 1 NSCLCs who underwent a total of 49 thermal ablations. The primary outcomes measured were 5-year overall survival (OS), lung-cancer specific survival (CSS), and progression-free survival (PFS). <br /><br />The study found that all ablation procedures were technically successful and no deaths occurred within 30 days after the procedure. The OS at 12 months follow-up was 94.7%, and the mean PFS was 48.4 months. Recurrent disease was found in only 1 out of 49 ablated lesions, approximately 27 months after the thermal ablation. The 5-year OS after the initial ablation treatment was 63.1%, and the lung-CSS was 94.7%. <br /><br />Complications were assessed based on the Society of Interventional Radiology classification system, and pneumothorax requiring hospitalization and intrapleural catheter occurred in 2 out of 49 ablations, both after microwave ablation. <br /><br />The study concludes that image-guided thermal ablation is a safe procedure for treating stage 1 NSCLC, with excellent cancer-specific and progression-free survival rates. It is particularly beneficial for patients who are not medically suitable for surgical resection or have compromised pulmonary reserve. The procedure can be repeated efficiently if patients develop multiple primary lung cancers.

Asset Subtitle

Soheil Kooraki

Meta Tag

Speaker Soheil Kooraki

Topic Early-Stage NSCLC: New Technology & Innovations

Keywords

long-term outcomes

medically inoperable patients

stage 1 NSCLC

image-guided thermal ablation

5-year overall survival

lung-cancer specific survival

progression-free survival

ablation procedures

complications

surgical resection