2023 World Conference on Lung Cancer (Posters)-EP07.03. Nodal Upstaging in Uniportal VATS Lobectomy for Early-Stage Lung Cancer: Is It Fair?

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This study presented the results of a retrospective observational longitudinal study analyzing patients who underwent uniportal video-assisted thoracoscopic surgery (u-VATS) lobectomy for early-stage lung cancer. The primary objective of the study was to assess the nodal upstaging rate in u-VATS lobectomy and compare it to other minimally invasive techniques.<br /><br />A total of 160 patients with clinically early-stage lung cancer were included in the analysis. The mean operative time was 113.6 minutes, and the mean chest tube duration was 3.4 days. The 30-day morbidity and mortality rates were 13.1% and 0%, respectively. The mean number of harvested nodes was 7.6. The nodal upstaging rate was 14.4%, with 8.7% of patients transitioning from N0 to N1 and 5.6% from N0 to N2. The 1-year nodal recurrence rate was 5%.<br /><br />The authors concluded that u-VATS, when performed in experienced tertiary centers, can provide satisfactory node dissection with low morbidity and mortality rates. They also found that the nodal upstaging rate in u-VATS lobectomy was comparable to other minimally invasive approaches. These findings suggest that u-VATS is a safe and effective approach in surgical oncology.<br /><br />The study also provided demographic, preoperative, operative, and postoperative details of the enrolled patients. The cohort consisted of a slightly higher proportion of female patients (49.4%), with a mean age of 69.8 years. About 46.3% of patients had a history of smoking, and various comorbidities were observed in the cohort. The most common tumor location was the right upper lobe (34.4%), and the most common histology was adenocarcinoma (65.6%).<br /><br />In summary, this study demonstrated that u-VATS lobectomy can achieve satisfactory nodal dissection in early-stage lung cancer, with comparable nodal upstaging rates to other minimally invasive approaches. It highlights the importance of thorough preoperative nodal evaluation and the potential of u-VATS as a safe and effective surgical technique in the management of early-stage lung cancer.

Asset Subtitle

Riccardo Orlandi

Meta Tag

Speaker Riccardo Orlandi

Topic Early-Stage NSCLC: Limited Resections & Minimally Invasive Approaches

Keywords

retrospective study

u-VATS lobectomy

early-stage lung cancer

nodal upstaging rate

minimally invasive techniques

morbidity rate

mortality rate

harvested nodes

tertiary centers

surgical technique