2023 World Conference on Lung Cancer (Posters)-EP14.03. PULS - An International Collaboration for Collection and Assessment of Data from Patients with PUL Monary Artery Sarcoma

EP14.03. PULS - An International Collaboration for Collection and Assessment of Data from Patients with PUL Monary Artery Sarcoma - PDF(Slides)

Back to course

Pdf Summary

This document outlines the aims and methods of an international multicenter study called PULS, which focuses on pulmonary artery sarcoma (PAS). PAS is a rare disease with limited available data on treatment options, making decision-making challenging. The study aims to better understand the pathophysiology and management of PAS through the collection and assessment of data from patients diagnosed with the disease.<br /><br />The study involves six participating centers, which are collecting data from both retrospective and prospective cases of PAS. The dataset includes consecutive sarcoma patients intended to be treated between 1994 and 2022. The researchers will screen tissue and blood samples for specific biomarkers and investigate correlations with clinical outcomes. The goal is to identify potential prognostic parameters that can be used for diagnostic and prognostic purposes in routine clinical practice in the future.<br /><br />One of the key aims of the project is to combine information from different omics approaches and utilize multiple profiling methods to gain a comprehensive understanding of the disease. This approach will help identify new biomarkers for PAS and provide opportunities for further investigation in subsequent prospective studies.<br /><br />The document concludes by stating that while standardized therapy concepts for PAS are yet to be established, the data gathered so far suggests that surgery plays a central role in treatment, with a median overall survival of 22 months. Currently, all data sets and retrospective tissue samples are being analyzed.<br /><br />Overall, the PULS study aims to improve the understanding and management of pulmonary artery sarcoma through an international collaborative effort, combining diverse omics approaches, and identifying new biomarkers for diagnostic and prognostic purposes.

Asset Subtitle

Isabelle Opitz

Meta Tag

Speaker Isabelle Opitz

Topic Other Thoracic Malignancy

Keywords

PULS

pulmonary artery sarcoma

rare disease

treatment options

biomarkers

clinical outcomes

prognostic parameters

omics approaches

surgery

international collaborative effort