2023 World Conference on Lung Cancer (Posters)-P1.15. Dedicated Cardiovascular Screening in Lung Cancer Screening: Preliminary Results from the European 4-IN-THE-LUNG-RUN Trial

P1.15. Dedicated Cardiovascular Screening in Lung Cancer Screening: Preliminary Results from the European 4-IN-THE-LUNG-RUN Trial - PDF(Abstract)

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The study presented is a preliminary evaluation of the potential benefits of dedicated cardiovascular screening within a lung cancer screening program. The study included individuals between the ages of 60-79 with a smoking history of 35 pack-years or more. The participants underwent a single low-dose chest CT scan to assess for lung nodules and coronary calcifications. The Agatston score was used to categorize the participants' risk for cardiovascular disease, with categories including low risk, moderate risk, high risk, and very high risk. <br /><br />The results showed that one-third of the participants were at a significantly high risk for coronary heart disease (CHD), while half of the population were suitable candidates for preventive CHD treatment. Approximately 47% of participants were at low to moderate CHD risk. The study also identified 16% of individuals with a low CHD risk who would not require preventive medication according to existing guidelines. <br /><br />The study highlights the potential benefits of conducting dedicated cardiovascular screening within a lung cancer screening program. By identifying individuals at high risk for CHD, appropriate preventive measures can be implemented to reduce the risk of cardiovascular events. The study is part of the ongoing European 4-IN-THE-LUNG-RUN trial, which aims to enroll 26,000 participants and will provide further data on the benefits of dedicated cardiovascular screening.

Asset Subtitle

Matthijs Oudkerk

Meta Tag

Speaker Matthijs Oudkerk

Topic Screening & Early Detection: Maximising Screening Benefits

Keywords

cardiovascular screening

lung cancer screening program

smoking history

low-dose chest CT scan

coronary calcifications

Agatston score

coronary heart disease

preventive medication

CHD risk

European 4-IN-THE-LUNG-RUN trial