2023 World Conference on Lung Cancer (Posters)-P1.26. Harmonized Maximum Standardized Uptake Value as an Indicator for Sublobar Resection: A Multicenter Retrospective Study

P1.26. Harmonized Maximum Standardized Uptake Value as an Indicator for Sublobar Resection: A Multicenter Retrospective Study - PDF(Slides)

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This study aimed to determine if the harmonized maximum standardized uptake value (iSUVmax) measured using different PET/CT scanners at multiple institutions can be used as a predictive indicator for pathological noninvasive lung cancer. The study included patients with clinical stage I non-small cell lung cancer (NSCLC) who underwent preoperative CT and PET/CT at four different institutions between January 2013 and December 2014.<br /><br />The results showed that iSUVmax was a better indicator for predicting pathological noninvasive lung cancer compared to the C/T ratio. The iSUVmax values were calculated using a commercially available software to make SUVmax values comparable across different institutions and scanners. The study also found that there was a small difference in the classification between iSUVmax and SUVmax with a cut-off value of 1.433.<br /><br />The prognosis after surgery was excellent regardless of whether iSUVmax or SUVmax was used, with high 5-year recurrence-free survival and overall survival rates in both groups.<br /><br />The study concluded that the use of SUVmax measured at each institution as an indicator for sublobar resection is acceptable and convenient, even in multicenter settings.<br /><br />Overall, this multicenter retrospective study suggests that iSUVmax can be a useful indicator for predicting pathological noninvasive lung cancer and can be used in clinical practice for guiding treatment decisions.

Asset Subtitle

Masahiro Adachi

Meta Tag

Speaker Masahiro Adachi

Topic Early-Stage NSCLC: More Minimally Invasive Approaches

Keywords

harmonized maximum standardized uptake value

iSUVmax

PET/CT scanners

predictive indicator

pathological noninvasive lung cancer

clinical stage I non-small cell lung cancer

C/T ratio

SUVmax values

recurrence-free survival

sublobar resection