2023 World Conference on Lung Cancer (Posters)-P1.26. Increased Risk of Death from Other Causes After Lobectomy Compared with Sublober Resection in Lung Cancer Patients

P1.26. Increased Risk of Death from Other Causes After Lobectomy Compared with Sublober Resection in Lung Cancer Patients - PDF(Slides)

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The JCOG0802/WJOG4607L trial found that segmentectomy had a higher overall survival rate compared to lobectomy for small-sized peripheral lung cancer, despite a higher local recurrence rate. This was attributed to a lower rate of death from other causes in the segmentectomy group. The objective of this study was to compare the risk of death from other causes after lobectomy and sublobar resection in lung cancer patients. The results showed that the risk of death from other causes was higher after lobectomy than after sublobar resection. This finding could potentially influence the choice of surgical procedure for lung cancer patients. However, further validation with larger scale data is needed, along with consideration of other background factors. In a matched cohort analysis, the sublobar group had a significantly longer overall survival than the lobectomy group. The proportion of respiratory diseases as the cause of death was higher in the lobectomy group compared to the sublobar group. Subgroup analysis revealed that factors associated with an increased risk of death after lobectomy were being female, age 65 or older, having no comorbidities, and having lower lobe disease. The study also compared patient characteristics and overall survival between the sublobar and lobectomy groups. The results suggest that lung preservation through sublobar resection may reduce the risk of death from other causes in lung cancer patients.

Asset Subtitle

Masayuki Nakao

Meta Tag

Speaker Masayuki Nakao

Topic Early-Stage NSCLC: More Minimally Invasive Approaches

Keywords

segmentectomy

lobectomy

overall survival rate

small-sized peripheral lung cancer

local recurrence rate

death from other causes

sublobar resection

risk of death

surgical procedure

lung preservation