2023 World Conference on Lung Cancer (Posters)-P2.31. Characterization of Survival Disparities among Asian Pacific Islander (API) Subgroups in Stage IV NSCLC in California

P2.31. Characterization of Survival Disparities among Asian Pacific Islander (API) Subgroups in Stage IV NSCLC in California - PDF(Slides)

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A study conducted by Robert Hsu at the University of Southern California evaluated the frequency and survival differences among Asian Pacific Islander (API) subgroups in Stage IV Non-Small Cell Lung Cancer (NSCLC) in California. The study found significant disparities among these subgroups in terms of sociodemographic, tumor, health insurance, comorbidity, treatment, and metastatic characteristics.<br /><br />The results showed that Pacific Islanders had the highest incidence and mortality rates, while South Asians had the lowest. Japanese had the highest percentage of patients diagnosed at age 75, while Other Southeast Asians and Pacific Islanders had the lowest percentages. Japanese had the highest percentage of males diagnosed, while South Asians had the lowest. Chinese had the highest percentage of known never smokers, while Pacific Islanders and Japanese had the lowest percentages.<br /><br />South Asians had the highest percentage of high socioeconomic status, while Other Southeast Asians had the lowest. Other Southeast Asians had the highest percentage of known government insurance, while Japanese had the highest percentage of private insurance. Chinese had the highest percentage of known adenocarcinoma histology subtype, while Japanese had the lowest.<br /><br />South Asians had the highest percentage of receiving chemotherapy, while Other Southeast Asians had the highest percentage of not receiving systemic treatment. Koreans and Other Southeast Asians had the highest percentage of known T4 tumor size, while Koreans and Other Southeast Asians had the highest percentage of known N3 nodal stage.<br /><br />In terms of overall survival (OS), South Asians had the highest 12-month OS, while Japanese, Pacific Islanders, and Other Southeast Asians had the lowest. Japanese had a significantly higher mortality risk compared to Chinese, even after adjusting for tumor characteristics. Pacific Islanders and Other Southeast Asians also had higher mortality risks.<br /><br />The study concludes that there are significant differences among API subgroups in Stage IV NSCLC in terms of sociodemographic factors and survival. It emphasizes the need to disaggregate these subgroups in order to better understand and provide appropriate care to these patients. The study acknowledged the support of various organizations in collecting cancer incidence data.

Asset Subtitle

Robert Hsu

Meta Tag

Speaker Robert Hsu

Topic Global Health, Health Services & Health Economics: Real World Data

Keywords

Robert Hsu

University of Southern California

study

Asian Pacific Islander

API subgroups

Stage IV Non-Small Cell Lung Cancer

California

disparities

sociodemographic factors

tumor characteristics