2024 Asia Conference on Lung Cancer (ACLC) - Poster & ePosters-PP02.37

PP02.37 - Takuya Nagashima

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The study "Analysis of local recurrence cases after segmentectomy for primary lung cancer" by Takuya Nagashima and colleagues examines 790 patients who underwent segmentectomy for primary lung cancer at Kanagawa Cancer Center in Yokohama, Japan, between January 2010 and April 2023. The goal was to analyze local recurrence to determine optimal treatment strategies.<br /><br />**Findings:**<br /><br />1. **Recurrence Rates and Timing:**<br />   - Out of 790 patients, 44 (5.6%) experienced a recurrence.<br />   - Local recurrence occurred in 10 patients (1.3%).<br />   - The median time to recurrence was 14 months, ranging from 2 to 130 months.<br /><br />2. **Recurrence Sites:**<br />   - Surgical margin: 3 cases.<br />   - Same lobe or hilar lymph node: 3 cases.<br />   - Mediastinal lymph node: 4 cases.<br /><br />3. **Treatment Approaches:**<br />   - Surgery was performed in 2 cases.<br />   - Radiotherapy was applied in 6 cases.<br />   - Combined radiotherapy and anticancer drugs in 1 case.<br />   - Observational management in 1 case.<br /><br />4. **Prognosis Post-Recurrence:**<br />   - No re-recurrence was observed in patients who underwent surgery (2 cases) and radiotherapy/chemotherapy (3 cases).<br />   - Re-recurrence occurred in 4 patients who received radiotherapy and 1 who was under observation.<br /><br />The study suggests surgery is effective for cases with local recurrence, particularly at the surgical margin or within the same lobe. However, radiotherapy serves as another viable option, especially in patients where surgery might be challenging due to the patient's overall health or specific characteristics of the recurrence.<br /><br />This analysis indicates a relatively low rate of local recurrence post-segmentectomy and highlights potential treatment paths when recurrence does occur, suggesting a flexible approach dependent on individual patient circumstances and recurrence specifics.

Keywords

local recurrence

segmentectomy

primary lung cancer

Kanagawa Cancer Center

recurrence rates

treatment strategies

surgical margin

radiotherapy

prognosis

flexible approach