2024 Asia Conference on Lung Cancer (ACLC) - Poster & ePosters-PP02.49

PP02.49 - Jun Suzuki

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This document explores a retrospective study on surgical outcomes for small-sized solid lung cancers, specifically comparing lobectomy and segmentectomy, conducted by the Department of Surgery at Yamagata University, Japan. The analysis covers surgeries performed between January 2014 and December 2021.<br /><br />Key findings include data from 234 patients with non-small cell lung cancer (radiological pure-solid tumors measured at 2 cm or less, cT1a or cT1b). Surgical interventions included 131 lobectomies and 103 sublobar resections (79 being segmentectomies and 24 wedge resections).<br /><br />The study reveals comparable postoperative outcomes between lobectomy and sublobar resection, specifically segmentectomy, with slight differences. While lobectomy remains a standard procedure, the overall survival (OS) and freedom from recurrence are similar between the two methods. Segmentectomy showed a 5-year OS of 91.2% and a recurrence-free survival of 98.5% compared to lobectomy's OS of 85.8% and recurrence-free survival of 94.4%.<br /><br />Despite the generally comparable outcomes, segmentectomy showed less blood loss and slightly shorter operation times, though lobectomy had a higher rate of postoperative complications. The study emphasizes that choice of surgery should consider multiple factors, including patient gender, age, smoking history, BMI, and tumor characteristics such as diameter and cancer stage.<br /><br />The retrospective nature and limited case numbers of the study necessitate cautious interpretation, but it supports the feasibility of segmentectomy as a viable alternative to lobectomy in selected early-stage solid lung cancer cases. This data also indicates that segmentectomy might associate with a somewhat poorer prognosis compared to previous reports, emphasizing the need for careful surgical decision-making.

Keywords

retrospective study

surgical outcomes

small-sized lung cancers

lobectomy

segmentectomy

Yamagata University

non-small cell lung cancer

postoperative outcomes

sublobar resection

surgical decision-making