2024 World Conference on Lung Cancer (WCLC) - Posters-P1.09A.01 The Effectiveness of Split-course Stereotactic Body Radiation Therapy in Treating Large Thoracic Cancer

P1.09A.01 The Effectiveness of Split-course Stereotactic Body Radiation Therapy in Treating Large Thoracic Cancer

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The document discusses a study on the effectiveness and safety of split-course Stereotactic Body Radiation Therapy (SBRT) for treating large thoracic cancers that are inoperable. Traditional single-course SBRT often leads to significant damage to normal tissues when used on large thoracic tumors. This study specifically targeted patients with tumors larger than 5 cm, including central, ultra-central tumors, and larger tumors in cases of pulmonary oligometastases. The primary aim was to enhance local tumor control while minimizing adverse side effects.<br /><br />Conducted by researchers from Harbin Medical University Cancer Hospital and the Fourth Hospital, the study investigated whether dividing the SBRT treatment into multiple courses could offer a safer and more effective approach for managing these large tumors. The study's materials and methods are summarized along with results depicted in figures, such as a timeline of the split courses and graphs illustrating changes in gross tumor volume in relation to treatment time.<br /><br />The referenced studies support this approach, emphasizing the need for systemic therapy-based split-course strategies and demonstrating the safety and efficacy of SBRT for large non-small cell lung cancer tumors over 5 cm.<br /><br />While the conclusion section is not provided here, the focus is evidently on achieving better local tumor control while reducing damage to healthy tissues, indicating a potentially favorable outcome for patients with inoperable large thoracic cancer through split-course SBRT.

Asset Subtitle

SiQi Tian

Meta Tag

Speaker SiQi Tian

Topic Metastatic NSCLC – Local Therapies

Keywords

split-course SBRT

large thoracic cancers

inoperable tumors

Harbin Medical University

tumors larger than 5 cm

local tumor control

adverse side effects

pulmonary oligometastases

non-small cell lung cancer

radiation therapy safety