2024 World Conference on Lung Cancer (WCLC) - Posters-P2.04A.07 Improving IPN Management Through CAD and Virtual Nodule Clinics: A Prospective, Observational Multicenter Study (PINPOINT)

P2.04A.07 Improving IPN Management Through CAD and Virtual Nodule Clinics: A Prospective, Observational Multicenter Study (PINPOINT)

Back to course

Pdf Summary

The PINPOINT study is an observational, multicenter research initiative aimed at improving the management of Incidental Pulmonary Nodules (IPNs) through the use of Computer Assisted Detection (CAD) and Virtual Nodule Clinics (VNC). Conducted across Europe, the study seeks to assess the clinical benefits and cost-effectiveness of these technological aids in a real-world setting.<br /><br />The study's main objectives are to evaluate the rate of early-stage lung cancer diagnosis with curative intent treatment and investigate the benefits provided by CAD and VNC. The CAD system assists in detecting, classifying, and measuring nodules on chest CT scans, potentially increasing the accuracy and rate of detection compared to traditional methods. Meanwhile, the VNC, facilitated by a nodule navigator, ensures adherence to follow-up protocols and guidelines by tracking patients with actionable IPNs according to the British Thoracic Society (BTS) guidelines.<br /><br />Eligible study participants include adult patients who have undergone chest CT scans for indications other than lung cancer suspicion, have at least one pulmonary nodule requiring follow-up, but have no history of diagnosed primary cancer in the last five years or known active systemic lung disease. Immunocompromised patients are also excluded due to potential risks of pulmonary infections.<br /><br />The research comprises both prospective and retrospective analyses. The prospective component assesses the transition in lung cancer diagnosis stages, exploring clinical management trends, adherence to guidelines, psychological impact, and the eligibility for lung cancer screening. The retrospective aspect evaluates the frequency and characteristics of CAD-detected nodules that correspond to lung cancer diagnosis within five years compared to traditional radiologist interpretations. The study plans to begin enrolling up to 1,000 patients in early 2025 across eight hospitals in four countries, with financial support provided by AstraZeneca.

Asset Subtitle

Bo Willems

Meta Tag

Speaker Bo Willems

Topic Screening & Early Detection

Keywords

PINPOINT study

Incidental Pulmonary Nodules

Computer Assisted Detection

Virtual Nodule Clinics

early-stage lung cancer

British Thoracic Society

chest CT scans

prospective analysis

retrospective analysis

AstraZeneca