2024 World Conference on Lung Cancer (WCLC) - Posters-P2.04B.02 Eight Year Outcomes of a Multidisciplinary Lung Cancer Screening Program at a Large Community Centre in Canada

P2.04B.02 Eight Year Outcomes of a Multidisciplinary Lung Cancer Screening Program at a Large Community Centre in Canada

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The presentation "Eight Year Outcomes of a Multidisciplinary Lung Cancer Screening Program" by Dr. Marc Ossip highlights the efficacy of a lung cancer screening initiative at the William Osler Health System in Canada. Established in 2012, the program focuses on screening high-risk patients using low-dose chest CT scans (LDCT), recognized for reducing lung cancer mortality. The study encompassed patients from 2012 to 2019, with follow-ups until April 2023, making it the longest-running multidisciplinary screening initiative in the country outside a research or pilot context.<br /><br />During the eight-year period, the program screened 5,460 individuals, conducting a total of 14,048 LDCT scans, and achieved a retention rate of 71.7%. The median age of participants was 63 years, with males constituting 61%. Annually, the program recorded substantial growth, enrolling 683 new patients per year. Of the patients who underwent CT-guided biopsy, 52.4% of biopsies were malignant, indicating a significant success rate in early cancer detection. Predominantly, non-small cell lung cancer adenocarcinoma was identified.<br /><br />Surgical intervention data revealed 201 resections, with cancer confirmed in 93.2% of patients who had undergone pre-surgical biopsies. The majority of these involved lobectomies, illustrating efficient surgical management of confirmed cases. The overall cancer detection rate was 4.1%, predominantly identifying early-stage cancers which are critical for curative interventions. This detection rate significantly surpassed the 1.7% noted in the National Lung Screening Trial, suggesting a promising model for lung cancer screening within community hospitals.<br /><br />The program’s success highlights its potential as a template for similar initiatives, suggesting the need for further exploration into factors contributing to its high detection rate. Supported by a grant from AstraZeneca and the Lung Ambition Alliance, this initiative sets a benchmark for community-based cancer screening programs.

Asset Subtitle

Marc Ossip

Meta Tag

Speaker Marc Ossip

Topic Screening & Early Detection

Keywords

lung cancer screening

multidisciplinary program

low-dose CT scans

early cancer detection

William Osler Health System

non-small cell lung cancer

community hospitals

cancer mortality reduction

AstraZeneca grant

Lung Ambition Alliance