2024 World Conference on Lung Cancer (WCLC) - Posters-P2.17A.08 Trends in Pulmonary Embolism Outcomes Among Lung Cancer Patients: A Nationwide Analysis Across a Decade

P2.17A.08 Trends in Pulmonary Embolism Outcomes Among Lung Cancer Patients: A Nationwide Analysis Across a Decade

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The study analyzes trends in pulmonary embolism (PE) outcomes among lung cancer (LC) patients over a decade using the National Inpatient Sample data from 2012 to 2021. Lung cancer is a prevalent cancer in the U.S. and a significant cause of cancer-related deaths, with PE contributing to 10% mortality within LC patients. The research aims to evaluate whether current guidelines are effective and identify potential improvements.<br /><br />Key findings indicate that while the total hospital admissions for PE increased from 179,615 to 197,115, the percentage of LC patients admitted with PE decreased from 3.8% to 3.4%. Despite the decline in PE incidence among LC patients, their mortality rates have been rising, with decreasing usage of surgical interventions. Surgical interventions are typically reserved for high-risk PE cases. <br /><br />The study also reveals that PE patients with LC experienced longer hospital stays than those without LC, although the duration has declined over the years, from 5.7 days versus 5.1 days in 2012 to 5.1 days versus 4.4 days in 2021. Hospitalization costs for PE patients with LC rose from $53,588 to $61,441 from 2012 to 2021, with a similar increase for non-LC PE patients after inflation adjustments.<br /><br />The research concludes that despite a reduction in PE incidence among LC patients, increasing mortality rates coupled with higher healthcare utilization, and decreased surgical interventions suggest the need to reassess treatment guidelines. It emphasizes the importance of reviewing thromboprophylaxis protocols tailored for LC patients with PE to potentially reduce morbidity and mortality.

Asset Subtitle

Divya Solipuram

Meta Tag

Speaker Divya Solipuram

Topic Global Health, Health Services & Health Economics

Keywords

pulmonary embolism

lung cancer

mortality rates

National Inpatient Sample

surgical interventions

hospitalization costs

thromboprophylaxis protocols

healthcare utilization

treatment guidelines

cancer-related deaths