2024 World Conference on Lung Cancer (WCLC) - Posters-P3.01D.05 Gender Differences in Lung Cancer Incidence Among Patients Who Never Smoked Cigarettes: A Systematic Literature Review

P3.01D.05 Gender Differences in Lung Cancer Incidence Among Patients Who Never Smoked Cigarettes: A Systematic Literature Review

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This systematic literature review examines gender differences in lung cancer incidence among individuals who have never smoked, considering demographic factors such as age, race, and socio-economic status. The review includes ten studies conducted across Europe, Asia, and North America between 1960 and 2019. It highlights that women who have never smoked show higher lung cancer rates compared to men, particularly at younger ages and for adenocarcinoma, a specific type of lung cancer.<br /><br />The analysis reveals that although overall lung cancer incidence remains stable in women, it has decreased over time for men. Notably, young women, specifically those from certain racial/ethnic backgrounds like Black and Asian populations, face higher incidence rates compared to men. The data also suggests socio-economic factors play a role, as incidences increase among women with higher socio-economic status.<br /><br />The findings underscore the necessity for targeted research to understand the underlying causes of these disparities, aiming to refine screening strategies and improve outcomes for all at-risk individuals, regardless of smoking history. Public health policies could benefit from these insights by prioritizing lung cancer screening and preventive measures for identified high-risk groups.<br /><br />However, limitations are noted, including the small number of studies, geographical focus predominantly on Europe, Asia, and North America, and the exclusive inclusion of English-language studies, which could exclude relevant research from other regions.<br /><br />Overall, these findings prompt further investigation into global, demographic-specific data to facilitate equitable detection and prevention strategies for lung cancer, particularly for never-smokers. This could help inform public health policies and interventions tailored for women, younger age groups, and specific racial and ethnic populations.

Asset Subtitle

Daniela Molena

Meta Tag

Speaker Daniela Molena

Topic Risk Factors, Risk Reduction & Tobacco Control

Keywords

gender differences

lung cancer

never smoked

demographic factors

adenocarcinoma

socio-economic status

racial/ethnic disparities

screening strategies

public health policies

global data