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2024 World Conference on Lung Cancer (WCLC) - Post ...
P4.15A.01 Efficacy of Digital Therapeutics for the ...
P4.15A.01 Efficacy of Digital Therapeutics for the Perioperative Management in Patients with Lung Cancer: A Randomized Controlled Trial
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The study aimed to evaluate the efficacy of digital therapeutics (DTx) compared to traditional multidisciplinary management (MM) for the perioperative management of lung cancer patients undergoing minimally invasive lung surgery. Conducted as an open-label, single-center, non-inferiority, randomized controlled trial in China, the research included 186 patients, with 147 completing the study. Participants were randomly assigned to DTx-assisted management or traditional MM.<br /><br />The primary outcome was the pulmonary function recovery rate, measured by forced expiratory volume in the first second (FEV1) three weeks post-surgery. The study also assessed secondary endpoints including the duration of hospital stay, 90-day unplanned readmission rates, symptom scores, management efficacy, and patient satisfaction rates. Exploratory endpoints examined factors influencing postoperative lung function recovery.<br /><br />Results showed that the FEV1 recovery rate of the DTx group was not inferior to the MM group, with rates of 87.18% and 84.21% respectively. No significant differences were observed between groups in terms of postoperative hospitalization duration or 90-day unplanned readmission rates. DTx management significantly reduced the management time per patient compared to MM, taking an average of 1.48 minutes versus 16.67 minutes (p=0.001). After discharge, the occurrence of target symptoms like pain, coughing, and shortness of breath was lower in the DTx group (p=0.002). Patients with a higher education level benefited more from DTx in terms of FEV1 recovery (p=0.021).<br /><br />The study concludes that DTx offers a non-inferior alternative to MM in managing perioperative lung cancer patients, with benefits including shorter management times and effective symptom management post-discharge. This digitalized approach may serve as an alternative management mode for lung cancer surgery patients.
Asset Subtitle
Jinming Xu
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Speaker
Jinming Xu
Topic
Multidisciplinary Care: Nursing, Allied Health & Palliative Care
Keywords
digital therapeutics
multidisciplinary management
lung cancer surgery
minimally invasive surgery
pulmonary function recovery
randomized controlled trial
postoperative management
patient satisfaction
symptom management
China
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