2024 World Conference on Lung Cancer (WCLC) - Posters-P4.15B.01 Remote Exercise Program for Patients with Lung Cancer on Immune Checkpoint Inhibitors

Pdf Summary

The prospective study investigated the efficacy of a remote exercise program for patients with advanced lung cancer (LC) receiving immune checkpoint inhibitors (ICI). While advancements in LC treatment exist, patients frequently endure significant physical and psychological challenges impacting their quality of life and treatment outcomes. Exercise interventions have shown promise in reducing symptom burden and enhancing overall well-being, yet less than one-third of LC patients meet exercise guidelines, which include 150 minutes of weekly aerobic activity, strength, and balance-building activities.<br /><br />The study involved 14 patients aged around 70.5 years, with stages III and IV LC, undergoing treatments such as Pembrolizumab or Durvalumab. An initial assessment was conducted via WhatsApp, and personalized exercise regimens were developed by certified trainers. Over 12 weeks, patients participated in virtual weekly appointments, during which exercise intensities were adjusted. The program prescribed 3 to 5 hours of weekly workouts, integrating resistance, aerobic, and mobility exercises.<br /><br />Descriptive statistics and linear mixed models were used for data analysis. Results revealed significant improvements in the health-related quality of life (HRQOL) scores and symptom management, highlighting the program's positive impact. Despite limitations such as a small sample size, lack of a control group, and self-reported measures, the findings emphasize the importance of supervised remote physical activity for older patients, aligning with guidelines from reputable institutions.<br /><br />The study suggests potential significant benefits from integrating structured exercise regimens into LC patient care, which could complement conventional medical therapies, by not only managing symptoms and improving HRQOL but also potentially influencing treatment uptake and outcomes in advanced LC cases.

Asset Subtitle

Paulo Bergerot

Meta Tag

Speaker Paulo Bergerot

Topic Multidisciplinary Care: Nursing, Allied Health & Palliative Care

Keywords

remote exercise program

advanced lung cancer

immune checkpoint inhibitors

quality of life

exercise interventions

Pembrolizumab

Durvalumab

health-related quality of life

symptom management

supervised physical activity