2024 World Conference on Lung Cancer (WCLC) - Posters-P4.17D.03 Analysis of Lung Cancer Mortality Trends and Factors Impacting Years of Life Lost: A 20-Year Hospital-Based Cohort Study in São Paulo, Brazil.

P4.17D.03 Analysis of Lung Cancer Mortality Trends and Factors Impacting Years of Life Lost: A 20-Year Hospital-Based Cohort Study in São Paulo, Brazil.

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The study "Analysis of Lung Cancer Mortality Trends and Factors Impacting Years of Life Lost" conducted in São Paulo, Brazil, examines the mortality trends and factors influencing years of life lost (YLL) due to lung cancer over a 20-year period. The research utilizes data from 5,419 patients, sourced from the São Paulo State Hospital Cancer Registry (SPHCR), detailing differences in YLL based on factors such as gender, clinical stage, histological type, recurrence, and periods of time.<br /><br />Key findings from the study include:<br /><br />1. **Stage Influence**: Patients in stage IV lost approximately double the years of life compared to those in stage I, underscoring the significance of early detection.<br /><br />2. **Gender Disparities**: Females exhibited higher YLL compared to males, indicating potential differences in disease progression or healthcare access and management.<br /><br />3. **Histological Differences**: Small cell lung carcinoma (SCLC) and adenocarcinoma (ADN) patients had higher YLL compared to those with squamous cell carcinoma (SCC) and large cell lung carcinoma (LCLC).<br /><br />4. **Impact of Recurrence**: Patients at clinical stages I and II with or without disease recurrence had comparable YLL, suggesting recurrence management may neutralize its impact on life expectancy.<br /><br />5. **Stability Over Time**: The Annual Percent Change (APC) shows minimal variation in YLL over the 15-year period post-2005, indicating stable mortality rates and highlighting the need for consistent healthcare policies.<br /><br />The study emphasizes the importance of early detection, gender-specific healthcare strategies, and continuous surveillance to improve lung cancer outcomes. The analysis provides critical insights for policymakers and healthcare providers aiming to reduce lung cancer mortality and YLL.

Asset Subtitle

André Marcheti

Meta Tag

Speaker André Marcheti

Topic Global Health, Health Services & Health Economics

Keywords

lung cancer

mortality trends

years of life lost

São Paulo

early detection

gender disparities

histological differences

recurrence impact

healthcare policies

cancer outcomes