2024 World Conference on Lung Cancer (WCLC) - ePosters-EP.04C.06 Investigation on the Incidence and Risk Factors of Lung Cancer Among Chinese Hospital Employees

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The study conducted by Qing Liang, Zi-hao Chen, and Wen-zhao Zhong at the Guangdong Provincial People’s Hospital and Guangdong Lung Cancer Institute aims to identify the incidence and risk factors associated with lung cancer among Chinese hospital employees. It involved 2,633 employees aged 40 and above who underwent low-dose CT lung cancer screenings between January 2019 and March 2024. The study assessed demographic data, smoking history, diet, mental health, and PM2.5 exposure, especially for those in radiation-related occupations.<br /><br />The results revealed that the detection rate of suspicious pulmonary nodules was 9.84%, while the incidence rate of lung cancer, including adenocarcinoma in situ, was recorded at 5.43%. Notably, the incidence of lung cancer among the hospital employees studied was significantly higher than that among the general population at 9.84% versus 0.041%. The median age of onset was identified between 45 and 50 years, with a high-risk age group being those over 50.<br /><br />Despite the higher incidence rates, the study found that an increase in screening rates did not correspond to an increased detection rate of lung cancer over time, as more stable ground-glass nodules were observed without further progression. This suggests that current follow-up strategies may effectively manage these nodules without escalating into cancer.<br /><br />The study acknowledges that small sample sizes limit the ability to draw definitive conclusions about direct risk factors or the exact incidence in the broader population. Nevertheless, it highlights the critical role of increased CT screening rates in early detection and timely intervention of lung abnormalities. This research underscores the importance of targeted screening programs within high-risk groups, such as healthcare workers, to effectively manage and mitigate lung cancer risks.

Asset Subtitle

Qing Liang

Meta Tag

Speaker Qing Liang

Topic Screening and Early Detection

Keywords

lung cancer

Chinese hospital employees

low-dose CT screening

risk factors

pulmonary nodules

adenocarcinoma in situ

PM2.5 exposure

radiation-related occupations

early detection

high-risk groups