2024 World Conference on Lung Cancer (WCLC) - ePosters-EP.04D.04 COVID-19 and Vaccines: A Decade of Insight from China Onpulmonary Nodules Detection and Progression

EP.04D.04 COVID-19 and Vaccines: A Decade of Insight from China Onpulmonary Nodules Detection and Progression

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The e-poster titled “COVID-19 and Vaccines: A Decade of Insight from China on Pulmonary Nodules Detection and Progression” presents research analyzing the impact of COVID-19 and vaccinations on the detection and progression of pulmonary nodules. Authored by Wenjun Ye, Weizheng Zhang, Deliang Xiong, Hui Zhou, Yi Feng, Jianxing He, and Wenhua Liang, the study examines trends from 773,175 chest CT scans performed between January 2013 and December 2023. These scans were categorized into three groups: inpatients and two health examination cohorts. Critical periods studied include times surrounding COVID-19 vaccine rollouts and the pandemic outbreak.<br /><br />The study employed a fuzzy regression discontinuity design (FRD) to assess monthly nodule detection and progression rates in relation to specific COVID-19 events. The analysis revealed a consistent annual increase in the detection rate of pulmonary nodules, attributed primarily to the increased detection of small nodules under 5 mm, thereby causing a slight decrease in nodule progression rates. Importantly, the data demonstrated that the COVID-19 pandemic and associated vaccination efforts did not significantly affect the detection or progression rates of pulmonary nodules.<br /><br />This research provides crucial insights, suggesting that COVID-19-related events do not have a substantial impact on pulmonary nodule dynamics, offering guidance to clinicians and patients in managing lung health post-pandemic. The findings have broader implications for understanding COVID-19's long-term impact on pulmonary health and other body systems, aiming to support better health management practices in a post-COVID world. The study is distinctive for its extensive data collection and comprehensive examination of trends over a significant period marked by substantial global events.

Asset Subtitle

Wenjun Ye

Meta Tag

Speaker Wenjun Ye

Topic Screening and Early Detection

Keywords

COVID-19

vaccines

pulmonary nodules

detection

progression

fuzzy regression discontinuity

chest CT scans

health management

pandemic impact

lung health