2024 World Conference on Lung Cancer (WCLC) - ePosters-EP.04F.01 Challenges in Recruiting for a Randomized Controlled Intervention to Increase Lung Cancer Screening

EP.04F.01 Challenges in Recruiting for a Randomized Controlled Intervention to Increase Lung Cancer Screening

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The document details a clinical trial aimed at enhancing lung cancer screening (LCS) completion rates among UC Davis patients aged 50-80 with a history of smoking. Lung cancer remains the most fatal cancer, yet the screening rate is significantly low, at about 5% nationally. The trial, registered under ClinicalTrials.gov identifier NCT06351085, evaluates two interventions against standard care in increasing LCS among eligible patients. <br /><br />Initial eligibility assessment involved 3225 individuals randomizing into two intervention groups. Both groups had over 1300 contacts who needed further follow-ups, and initial interventions were initiated with 252 and 251 participants in each intervention arm respectively. Several challenges exist in recruiting patients, indicating a high percentage (87.7%) of contacted patients did not meet the U.S. Preventive Services Task Force (USPSTF) guidelines for LCS eligibility. A Navigator was engaged to assess eligibility through a structured protocol, resulting in only 12.3% of contacted patients being fully eligible for LCS.<br /><br />Key intervention arms include a Navigator-guided pathway, with one arm adding an educational video through the electronic patient portal. Despite these efforts, results show 45% LCS scheduling or completion rates among eligible participants, reflecting the structured intervention’s efficacy over unscheduled care.<br /><br />The discussion highlights reliance on outdated electronic health records for patients’ smoking history, necessitating direct contact for eligibility assessment. The use of educational materials aids in prompting LCS discussions. The trial is funded by the Victory Over Cancer Foundation, and future research will continue exploring the effectiveness of the Navigator-driven approaches in improving LCS uptake.

Asset Subtitle

Lucy Rios

Meta Tag

Speaker Lucy Rios

Topic Screening and Early Detection

Keywords

lung cancer screening

clinical trial

UC Davis

smoking history

NCT06351085

Navigator-guided pathway

educational video

USPSTF guidelines

electronic health records

Victory Over Cancer Foundation