2024 World Conference on Lung Cancer (WCLC) - ePosters-EP.07A.04 Risk Factor Analysis and Predictive Model for Air Leakage after Thoracoscopic Lung Wedge Resection

EP.07A.04 Risk Factor Analysis and Predictive Model for Air Leakage after Thoracoscopic Lung Wedge Resection

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The study titled "Risk factor analysis and predictive model for air leakage after thoracoscopic lung wedge resection" aimed to identify risk factors associated with air leakage (AL) and develop a predictive model to screen suitable patients for tubeless lung resection. Conducted by researchers from the Fujian Medical University Union Hospital in China, the study involved 2503 patients who had thoracoscopic pulmonary wedge resection between January 2015 and December 2020. <br /><br />Key findings indicated that 11.34% of patients experienced AL. The developed predictive model was based on factors such as age over 70, forced expiratory volume in 1 second (FEV1%) below 80%, the size and nature of the nodule (benign or malignant), and pleural adhesions (none, focal, diffuse). The model's effectiveness was evaluated through a C-index, showing strong discrimination with scores of 0.829 in the development data set and 0.833 in the validation data set.<br /><br />The study underscores the importance of a predictive model in guiding clinical decision-making, specifically for implementing a tubeless strategy, which can enhance postoperative recovery and reduce complications. This research is noted as the first large-scale multicenter study of its kind, focusing on predicting AL after lung wedge resection. The authors hope to refine the model further to aid in clinical practices.<br /><br />The overall aim was to facilitate a better understanding and preparation for potential postoperative complications in patients undergoing this surgical procedure, to ultimately improve patient outcomes and recovery experiences.

Asset Subtitle

Maohui Chen

Meta Tag

Speaker Maohui Chen

Topic Early-Stage Non-small Cell Lung Cancer

Keywords

air leakage

thoracoscopic lung wedge resection

predictive model

risk factors

tubeless lung resection

Fujian Medical University

postoperative recovery

C-index

pleural adhesions

multicenter study